{"product_id":"seqpure™-sanger-sequencing-cleanup-reagent","title":"SeqPure™ Sanger Sequencing Cleanup Resin","description":"\u003cp\u003e\u003cspan\u003e[shortdesc]\u003c\/span\u003eSeqPure™ is a high-performance post-reaction cleanup reagent designed for purification of Sanger sequencing reactions prior to capillary electrophoresis. Engineered as a direct drop-in replacement for BigDye\u003cspan\u003e™\u003c\/span\u003e XTerminator™, SeqPure™ delivers consistently strong signal intensity and clean electropherograms at a significantly lower cost per sample. \u003cspan\u003eSeqPure™ accelerates post sequencing purification by eliminating time-consuming wash steps, magnetic separation, centrifugation, pellet drying, and resuspension procedures\u003c\/span\u003e.\u003cspan\u003e[\/shortdesc]\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e[els_overview]\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0677\/4859\/3955\/files\/SeqPure_Sequencing_Purification_Resin.png?v=1779990117\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eSeqPure™ is a unique dual-function resin engineered for efficient removal of sequencing contaminants while preserving fluorescently labeled extension products in solution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eSeqPure™ Resin incorporates:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul data-spread=\"false\"\u003e\n\u003cli\u003e\u003cspan\u003eAn ion-exchange core designed to capture charged small-molecule contaminants\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eA size-exclusion outer layer that selectively limits access based on molecular size\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eThis architecture enables preferential sequestration of unwanted reaction components including:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul data-spread=\"false\"\u003e\n\u003cli\u003e\u003cspan\u003eUnincorporated dye terminators\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eResidual salts and buffer components\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSmall charged impurities\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eAt the same time, the larger fluorescent labeled ssDNA fragments remain suspended in the supernatant and are immediately available for electrokinetic injection.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eBy minimizing loss of sequencing products during cleanup, SeqPure™ helps maintain strong signal intensity while reducing background noise and dye artifacts that can interfere with electropherogram interpretation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"isSelectedEnd\"\u003e\u003cspan\u003eUnlike precipitation-based methods that rely on recovery and resuspension of DNA pellets, SeqPure™ performs cleanup directly in solution, simplifying workflow and improving reproducibility across samples. \u003c\/span\u003e\u003cspan\u003eThe result is a rapid and efficient purification process optimized for modern Sanger sequencing workflows.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eKey Benefits\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cspan\u003eDirect Drop-In Replacement\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eSeqPure™ integrates seamlessly into existing BigDye™ Xterminator™ workflows with no instrument modifications or protocol redesign required. Compatible with standard sequencing chemistries and capillary electrophoresis platforms.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eClean Signal, Excellent Read Quality\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eOptimized cleanup chemistry minimizes dye blobs, suppresses background noise, and improves electropherogram clarity for high-confidence sequencing results.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eStrong Signal Recovery\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eSeqPure™ maintains excellent recovery of extension products, producing high signal intensity and long readable sequence lengths.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eLower Cost per Sample\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eReduce sequencing cleanup costs without compromising data quality. SeqPure™ provides a cost-effective alternative for high-throughput and routine sequencing applications.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eFaster and More Convenient Workflow\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eUnlike magnetic bead purification or ethanol precipitation methods, SeqPure™ eliminates time-consuming wash steps, magnetic separation, centrifugation, pellet drying, and resuspension procedures.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe simplified workflow helps reduce hands-on time and improves laboratory throughput.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0677\/4859\/3955\/files\/SeqPure_Sanger_sequencing_purification.png?v=1779999741\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003eFig. 1 \u003cspan data-olk-copy-source=\"MessageBody\"\u003eElectropherogram of the result using SeqPure\u003cspan\u003e™\u003c\/span\u003e\u003c\/span\u003e. \u003cbr\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0677\/4859\/3955\/files\/Xterminator.png?v=1779999740\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003eFig. 2 \u003cspan data-olk-copy-source=\"MessageBody\"\u003eElectropherogram of the result using BigDye\u003cspan\u003e™\u003c\/span\u003e X-terminator\u003cspan\u003e™\u003c\/span\u003e\u003c\/span\u003e. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003cspan\u003e[\/els_overview]\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e[els_protocol] \u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"col large-2\"\u003e\n\u003cp style=\"text-align: center;\"\u003e\u003cspan\u003e \u003cstrong\u003eSeqPure\u003cspan data-olk-copy-source=\"MessageBody\"\u003e™\u003c\/span\u003e Protocol:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: center;\"\u003e\u003cspan\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0677\/4859\/3955\/files\/SeqPure_User_Manual.pdf?v=1780002735\" target=\"_blank\"\u003e \u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0677\/4859\/3955\/files\/pdf-white-icon.png?v=1674963469\" width=\"97\" height=\"126\"\u003e \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan\u003e[\/els_protocol]\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e[els_sds]Customised SDS will be uploaded soon.[\/els_sds]\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"epochlifescience","offers":[{"title":"CS5869-4 (4 ml)","offer_id":55162016235811,"sku":null,"price":323.55,"currency_code":"USD","in_stock":true},{"title":"CS5869-40 (40 ml)","offer_id":55164789424419,"sku":null,"price":2676.1,"currency_code":"USD","in_stock":true},{"title":"CS5869-100 (100 ml)","offer_id":55164790571299,"sku":null,"price":4357.65,"currency_code":"USD","in_stock":true},{"title":"CS5869-1600 (1600 ml)","offer_id":55164793159971,"sku":null,"price":26030.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0677\/4859\/3955\/files\/SeqPure_Resin_illustration.jpg?v=1779998490","url":"https:\/\/epochlifescience.com\/products\/seqpure%e2%84%a2-sanger-sequencing-cleanup-reagent","provider":"Epoch Life Science","version":"1.0","type":"link"}